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Can mask folate deficiency 5

Rethinking IL-6 and CRP: why they are more than inflammatory biomarkers, and why it matters

When CYP1A2 (Phase I) oxidizes an aromatic amine to its N-hydroxy derivative, and then O-acetyltransferase activity (catalyzed by the same NAT enzymes) transfers an acetyl group to the oxygen, it creates a highly reactive N-acetoxyarylamine that binds DNA

Xenobiotic perturbation of ER stress and the unfolded protein response

Most processed foods are extremely low in both and the kinds that do have fiber or antioxidants normally contain synthetic, added types

Notably, activation of TLR7 and TLR9 through this pathway induces type I interferon (IFN) responses, involving TRAF3 and IRF7